Protein ENGineering (PENG)
Key Takeaways
- Full and open competition - all businesses eligible to bid
- Work to be performed in ARLINGTON, VA
- Industry: Research and Development in Biotechnology (except Nanobiotechnology)
Contract Details
- Notice ID
- DARPA-PS-26-129
- Opportunity Type
- Solicitation
- Agency
- DEPT OF DEFENSE
- Sub-Agency
- DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)
- Office
- DEF ADVANCED RESEARCH PROJECTS AGCY
- Posted Date
- Friday, August 21, 2026
- Response Deadline
- Monday, October 19, 2026
- PSC Code
- AC12
- Set-Aside
- Full & Open Competition
- Place of Performance
- ARLINGTON, VA, 222032114
- Status
- Active
Description
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals for the development of a multifunctional, target-agnostic platform for precise, programmable editing of endogenous proteins. The goal of the Protein ENGineering (PENG) program is to transition proteome engineering from a collection of isolated, bespoke tools into a universal, software-defined discipline. The PENG program will establish a comprehensive, integrated platform composed of modular targeting, generalizable effector chemistries, and multiplexed control systems. Rather than developing isolated, target-specific tools, performers will integrate novel splicing, ligation, and co-translational techniques to directly recognize, modify, and rewrite endogenous proteins within complex biological archite
Why This Opportunity Matters
The Department of DEFENSE is actively seeking qualified contractors for research and development in biotechnology (except nanobiotechnology) in ARLINGTON, VA.
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