TECHNOLOGY LICENSING OPPORTUNITY: SignalGen

A platform that predicts the right signal peptide for a specific protein Many medicines, vaccines, and biotechnology products rely on proteins reaching the right cellular compartment or secretion outside a cell. Whether a protein gets there in enough quantities depends on its signal peptide or leader sequence. Scientists can identify many existing signal peptides, but predicting which one will work best for a specific protein remains difficult. SignalGen uses generative AI to predict the signal peptide most likely to guide a protein to the right location. To make that prediction, it considers the protein, where it needs to go, and the organism it comes from. This approach gives researchers a new way to improve protein expression for medicines, vaccines, and biotechnology products. Overview