Immune Mechanisms of Protection Against Mycobacterium tuberculosis Center (IMPAc-TB)

Introduction The National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), of the Department of Health and Human Services (DHHS) supports research related to the basic understanding of microbiology and immunology leading to the development of vaccines, therapeutics, and medical diagnostics for the prevention, treatment, and diagnosis of infectious and immune-mediated diseases. NIAID supports a robust program in basic immunology that includes detailed analyses of human immune responses to pathogenic infections and/or vaccines. NIAID also has a key role in basic, translational and clinical studies to further the understanding of Mycobacterium tuberculosis infection and disease in people living with or without HIV. Furthermore, NIAID provides several