TECHNOLOGY LICENSING OPPORTUNITY: Platform to Accelerate Discovery of Tailored Industrial Enzymes (PAD-TIE)

NREL and Los Alamos National Laboratorys PAD-TIE platform is an advanced screening system designed to accelerate the discovery and optimization of enzymes that break down polyethylene terephthalate (PET), one of the most widely used plastics. The Challenge: Traditional enzyme development is slow and requires testing individual enzymes under controlled conditions. PAD-TIE overcomes this limitation by simultaneously screening tens of thousands of enzyme variants under industrially relevant conditions for PET degradation. How it Works: Unlike conventional methods, PAD-TIE evaluates enzyme efficiency, stability, and production potential in a single process, ensuring that only the most viable candidates move forward. Validated in lab-scale bioreactors that replicate industrial recycling environ